Glucagon-like peptide-1 (GLP-1) is a peptide hormone that is released from the intestines in response to food intake. It plays a key role in regulating blood sugar levels by stimulating insulin release from the pancreas and inhibiting glucagon release. GLP-1 also helps to slow gastric emptying and promote feelings of fullness, making it an important factor in appetite control and weight management. Research in the area of GLP-1 has shown promise for the treatment of type 2 diabetes, as medications that mimic the effects of GLP-1 can help to lower blood sugar levels and improve insulin sensitivity. These medications are also being studied for their potential role in treating obesity, as they have been shown to reduce appetite and promote weight loss. Overall, research on GLP-1 continues to uncover the various ways in which this hormone can be targeted to improve metabolic health and treat conditions such as diabetes and obesity.